ゲノム情報科学研究教育機構  アブストラクト
Date April 23, 2009
Speaker Prof. Andrei Doncescu, LAAS-CNRS, France
Title Cancer Diagnosis by Abductive Reasoning
Abstract A diagnosis of cancer therapy is one of the most difficult experiences we can face due to the complex decisions on treatment with potentially life-threatening illness. The prediction of the cancer evolution in a frame of personalized therapy requests an exhaustive analysis of a patient profiles by efficient machine learning techniques. Using techniques as Inductive Logic Programming (ILP) which can find hypotheses that account for given observations with a background theory. The Hypothesis Finding applied on a relational database containing 250 profiles of cancer patient : relapse (or recover), emergence of 5 proteins SC35, 9G8, hnRNPA1, ASF-SF2 and SRp20 as well as the clinical information for each patient figure out several causal relations between treatment and the life extension.

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